Axialtrac – Greatest advancement to Flexion-Distraction in the past 50 years!

We have added the most advanced piece of equipment that improves on the existing gold standard for non-invasive disc decompression.

There are only a few in the state of Illinois and make treatment times cut by 30% without any risk.  A perfectly safe inexpensive, fast way of getting away from certain surgery.  Here is a link to the most advanced methodology in existence for treatment of herniated disc with or without stenosis.

Axial Trac is the greatest advancement to Flexion-Distraction in the past 50 years!

Axialtrac is Now at Lansing Chiropractic Clinic in Lansing Illinois

Axialtrac is Now at Lansing Chiropractic Clinic in Lansing Illinois

Axial Trac is a true hybrid chiropractic table. It’s an adjusting table, a flexion-distraction table, and a decompression table. Axial Trac is the all in one chiropractic table to meet your needs.

Axial Trac ™ employs a new technology patented by W. Patrick Danzey, D.C. This chiropractic table combines variable amounts of long axis (axial) traction with each flexion stroke. The hallmark of Axial Trac™ is a sliding upper pelvic section that is mechanically forced into distraction as the table is flexed. The traction handle is fixed to a non-sliding portion of the pelvic section so it does not move away from the doctor.

There are three electric motors; one for table elevation up to 34”, one for spring tension and one to pre-select the amount of long axis traction. A multi-position headpiece is standard. Cervical drop, thoracic drop, lumbar drop and break away thoracic sections are available. Dr. Danzey has been utilizing flexion distraction for 25 years and realized the need for on demand additional traction. The technique is performed manually, allowing the amount of additional traction delivered with each flexion or lateral flexion stroke to be determined by the doctor’s feel and the patient’s tolerance. Table calibration allows the doctor to record the amount of enhanced flexion distraction given on each visit. The Axial Trac™ chiropractic table combines the best aspects of flexion distraction and spinal decompression in one multipurpose adjusting table.

The technique is highly specific allowing the doctor to target individual spinal levels and right or left sides. This is accomplished utilizing manual contact and lateral flexion. The design goal was to maintain this level of target site specificity while being able to deliver up to three times more traction than a conventional flexion distraction table.

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Reviews of Lansing Chiropractic Clinic & Wellness Medical (Illinois) on the net…

We just want to say thank you to all of our patients that have given us terrific feedback of our office over the decades.  Also, many ask where they can post their reviews about us.   Here’s the online list!  Feel free to stop in our office to view our binders full of written patient reviews.  Please click the following links to see how our patients have reviewed Lansing Chiropractic Clinic & Wellness Medical on the net…

Zocdoc Reviews –                                   

Yellowbot Reviews –                                        

Kudzu Reviews –                                            

Wellness Reviews –

Yelp Reviews –                                                     

Google + Reviews –     


If you would like to give us a review please add yours to any of those sites or visit Facebook to see reviews from our Facebook Fans.

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Out of your hands – Carpal Tunnel Syndrome (CTS) – published in NWI.COM

Your fingers tingle and feel numb. Pain encircles your wrist and radiates all the way up your arm. The tingling, numbness and pain wake you up at night. Tennis players can have these symptoms. So can computer operators, grocery store cashiers, reporters, assembly line workers, secretaries, fast food cooks and jackhammer operators.

This diverse group of people may work at very different jobs in vastly different settings, but it shares one job hazard – repetitive, especially twisting, motion of the wrist and forearm that can lead to a condition called Carpal Tunnel Syndrome….

“When the wrist is twisted or subjected to a repetitive motion, the bones press against the nerve, causing inflammation or swelling. Fluid can build up in the carpal tunnel area. All that makes the already tight space even tighter and further compresses the nerve. In some cases, the carpal or wrist bones can become partially dislocated or misaligned, said Timothy Durnin, a chiropractic physician at the Lansing Chiropractic Clinic, Ltd.  All that can lead to those annoying, painful symptoms of CTS. And as the symptoms increase, even picking up a can of soda pop may become nearly impossible, Durnin said. That clumsiness is often what brings patients in for treatment, Dreyfuss and Durnin said.”

See full article by clicking the link below…

People on the Move – published in NWI.COM

Dr. Timothy Durnin has been accepted as a member of the American Association of Spine Physicians. This is an international organization of neurosurgeons and chiropractic physicians dedicated to improving the quality of spine care through cooperative and conservative efforts.”

A Shot in the Arm – published in NWI.COM

“Those who don’t get inoculated may wind up with a low-grade fever (below 101 degrees), chills and fatigue, among other symptoms, in December or January, health officials said. The bout could last up to three weeks, said Dr. Timothy Durnin, a chiropractor at Complete Wellness Medical Center in Lansing. [currently Lansing Chiropractic Clinic and Wellness Medical] It may feel like last year’s flu, but it isn’t, he said. ‘These viruses are smart. They mutate. Each year, it’s a new virus,’ he said. Also available are pneumonia vaccinations, which protect against viral strains of the disease. Health officials recommend them for anyone over age 65 and call it “a lifetime dose.” The inoculation is available for younger people, but lasts only 10 years.”

See full article by clicking the link below…

Contact Us for more information!

18037  Torrence Avenue  Lansing, IL  60438

Phone:  708-895-3228     Fax:  708-895-1057

Our clinic is located in the south suburbs of Chicago, one mile south of I 80/94 on Torrence Avenue in downtown Lansing. We have been in the same location since 1953, and employ a multidisciplinary approach to holistic health care.

Our mission at Lansing Chiropractic Clinic and Wellness Medical, S.C. is to provide affordable high-quality care to people of all ages. We strive to not only correct a person’s health problems, but to educate and enlighten people so that they do not encounter similar problems in the future.

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Sports Injuries – Part 2

Although there is no such thing as a “safe” sport, highly competitive sports, such as football, weightlifting, gymnastics, and wrestling, pose particularly higher risks of injuries, especially among children.

According to experts, as much as 20 percent of all sports-related injuries involve the lower back or neck. Running and weightlifting, and other sports that involve repetitive impact, expose children to a high risk for lumbar (lower back) injuries. Contact sports, such as soccer and football, expose the cervical spine, or neck, to injury. More than one-third of all high school football players sustain some type of injury. Soccer participants are easy candidates for mild to severe head traumas, neck injuries, cervical spine damage, headache, neck pain, dizziness, irritability, and insomnia. Heading the ball, the act of using the head to re-direct the soccer ball, has been linked with cervical injuries in children and adults. The trampoline and gymnastics also present significant risks for spinal cord injuries from unexpected and brute falls or contact with hard surfaces.

Here’s a look at some of the other common injuries by sport:

  • Bicycling – Poor posture can greatly increase your risks of a back injury during cycling. When riding a bike, your lower back is constantly flexing sideways and up and down. Upper back injuries can involve the flexing of the neck. And the bumps and jars incurred on the road during cycling can wreak havoc and possible compression injuries to your spine.

  • Golf – Common injuries incurred during the sport of golf usually involve muscle sprains and strains to the lower back.

  • Running/jogging – Running and jogging puts a great deal of stress on your back, since the constant pounding against a hard surface can jar, and possibly compress, structures such as vertebrae, joints, and discs.

  • Skiing – Skiing involves a great deal of twisting and turning motions, as well as jarring landings, all of which can cause muscle sprains and strains and in some cases, minor spinal fractures.

  • Swimming – Swimmers are known to incur lower back injuries. Motions such as the crawl or breaststroke can cause the lumbar region to be hyperextended. If the swimmer is not properly conditioned or warmed up, the hyperextension sometimes doesn’t subside.

  • Tennis – “Tennis elbow” is a layman’s term for pain on the lateral, or outside part of the elbow, on or near the bony protrusion. Tennis elbow is caused when the tendon from the elbow bone tears or is ruptured. It is no surprise that professional tennis players can become inflicted with this with all of the stress and strain they place on the joint during play. In addition, tennis players are in constant motion, and the repeated twisting and trunk rotations can cause injuries. Shoulder injuries and turned ankles and knees also are common. The act of serving the ball also has been shown to hyperextend the lower back, and possibly compress discs.

  • Weight lifting/body building – Body builders are at a significant risk for a host of serious back, shoulder, neck, and knee injuries. Resistance training has been known to cause muscle sprains and strains, ligament and tendon injuries, and in some cases, stress fractures (also called spondylolysis). Older people seem to be at higher risk since their bones and discs are more brittle.

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Sports Injuries – Part 1

Participation in sports or exercise is an important step in maintaining your health. Exercise strengthens your heart, bones, and joints and reduces stress, among many other benefits.

Unfortunately, injuries during participation in sports are all too common. Often, these injuries occur in someone who is just taking up sports as a form of activity, doesn’t use proper safety equipment, or becomes overzealous about the exercise regimen.

The more commonly injured areas of the body are the ankles, knees, shoulders, elbows, and spine. Remember that you should discuss any exercise program with your doctor of chiropractic before undertaking such activities.

Strains and Sprains
Although bones can sometimes be fractured with acute sports injuries, the most commonly injured structures are the muscles, tendons, and ligaments. Tendons attach muscles to bones, and ligaments attach one bone to another.

An acute twisting or overextension of a joint can lead to tears of muscles and tendons, called “strains,” and tears of ligaments result in “sprains.” These tears range from mild to severe. In mild injuries, just a few fibers are torn or stretched. Severe injuries, where there is a tear through the full thickness of the structure, are most often considered unstable injuries and frequently require surgical intervention. The intervertebral disc, a ligament between the vertebrae of the spine that works as a shock absorber, can also be torn, resulting in a disc bulge and/or herniation.

Ankle sprains most often involve tears of one or more of the ligaments along the outside of the ankle. Knee ligaments, including the larger external supportive ligaments and the smaller internal stabilizing ligaments, can also be torn. The cartilage on the back of the patella (knee-cap) can also become eroded from overuse, leading to a condition termed chondromalacia patella.

In those who are training too much, overuse of a particular joint or joints in the body can result in pain and dysfunction. These injuries are called “overuse syndromes.” A common overuse injury is tendinosis, also called tendinitis. In this condition, the tendon becomes inflamed from repetitive use. In the shoulder, the rotator cuff (a complex of muscles that stabilizes and moves the shoulder) becomes inflamed, resulting in rotator cuff tendinitis. Tennis elbow is another form of tendinitis that occurs along the outside of the elbow, most commonly in tennis players. In golfer’s elbow, the tendons on the inside of the elbow are affected.

Stress Fractures
Some athletes may experience a stress fracture, also called a fatigue fracture. This type of fracture occurs when an abnormal amount of stress is placed on a normal bone. This might occur in a runner who rapidly increases the amount of mileage while training for a race. Stress fractures also occur in people who begin running as a form of exercise but overdo it from the start, rather than gradually progress to longer distances.

One final common injury is worth mentioning, and that is shin splints. This overuse injury is caused by microfractures on the front surface of the tibia (shin bone). This is most often seen in runners, although other athletes can also be affected.

Diagnosis and Treatment
Sports injuries are most often diagnosed from the history of the activity that brought on the pain, along with a physical examination. In some cases, x-rays are necessary to rule out a fracture. Magnetic resonance imaging (MRI) and diagnostic ultrasound are also used in finding soft-tissue injuries, like tendinitis and sprains.

Fractures require the application of some stabilizing device, such as a cast, after the bone is put back into position. Rarely, surgical intervention is required. There is a relatively standard treatment protocol for most of the other overuse types of injuries. This protocol involves the following:

Generally no more than 48 hours of rest and/or immobilization is needed, depending on the severity of the injury. In most cases, the sooner the person becomes active after an injury, the more rapid is the recovery. In fact, long-term immobilization can sometimes be harmful to recovery. Your doctor of chiropractic will guide this process, as too early a return to activity, choosing the wrong type of activity, or excessive activity can be detrimental.

Ice can be helpful with pain reduction and tissue healing.

Compression of the area may reduce the amount of swelling from the injury. Your doctor of chiropractic will determine if this will be beneficial in your case.

Elevation of the injured arm or leg above the level of the heart is thought to be helpful in reducing swelling.

Pain relievers
Recent research has demonstrated that some nonsteroidal anti-inflammatory drugs may actually slow the healing process by restricting the body’s natural healing mechanisms, so they should be used sparingly.

Joint manipulation
Recent research has shown us that, in some cases, joint manipulation can be helpful with pain reduction and more rapid recovery. Your doctor of chiropractic will determine if this procedure will be helpful in your case.

A Word about Prevention
In many cases, sports injuries can be prevented. Proper conditioning and warm-up and cool-down procedures, as well as appropriate safety equipment, can substantially reduce injuries. Understanding proper techniques can also go a long way toward preventing injuries.
Sufficient water intake is also an important preventive measure.


Also see Lansing Chiropractic Clinic’s website for more information on sports injuries.

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What is Niacin?

Niacin (vitamin B3, nicotinic acid), Niacinamide


Niacin (vitamin B3, nicotinic acid), Niacinamide

Vitamin B3 is made up of niacin (nicotinic acid) and its amide, niacinamide, and can be found in many foods, including yeast, meat, fish, milk, eggs, green vegetables, and cereal grains. Dietary tryptophan is also converted to niacin in the body. Vitamin B3 is often found in combination with other B vitamins including thiamine, riboflavin, pantothenic acid, pyridoxine, cyanocobalamin, and folic acid.



These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.

Key to grades

 Grading rationale

High cholesterol (niacin)

Niacin is a well-accepted treatment for high cholesterol. Multiple studies show that niacin (not niacinamide) has significant benefits on levels of high-density cholesterol (HDL or “good cholesterol”), with better results than prescription drugs such as “statins” like atorvastatin (Lipitor®). There are also benefits on levels of low-density cholesterol (LDL or “bad cholesterol”), although these effects are less dramatic. Adding niacin to a second drug such as a statin may increase the effects on low-density lipoproteins. The use of niacin for the treatment of dyslipidemia associated with type 2 diabetes has been controversial because of the possibility of worsening glycemic control. Patients should check with a physician and pharmacist before starting niacin.

Pellagra (niacin)

Niacin (vitamin B3) and niacinamide are U.S. Food and Drug Administration (FDA)-approved for the treatment of niacin deficiency. Pellagra is a nutritional disease that develops due to insufficient dietary amounts of vitamin B3 or the chemical it is made from, tryptophan. Symptoms of pellagra include skin disease, diarrhea, dementia, and depression.

Atherosclerosis (niacin)

Niacin decreases blood levels of cholesterol and lipoprotein (a), which may reduce the risk of atherosclerosis (“hardening” of the arteries). However, niacin also can increase homocysteine levels, which may have the opposite effect. Overall, the scientific evidence supports the use of niacin in combination with other drugs (but not alone) to decrease cholesterol and slow the process of atherosclerosis. More research is needed in this area before a firm conclusion can be drawn.

Prevention of a second heart attack (niacin)

Niacin decreases levels of cholesterol, lipoprotein (a), and fibrinogen, which can reduce the risk of heart disease. However, niacin also increases homocysteine levels, which can increase this risk. Numerous studies have looked at the effects of niacin, alone and in combination with other drugs, for the prevention of heart disease and fatal heart attacks. Overall, this research suggests benefits of niacin, especially when combined with other cholesterol-lowering drugs.

Age-related macular degeneration (AMD)

Niacin may benefit the choroidal blood vessels, which underlie the region of the retina called the macula. Age-related macular degeneration (AMD) may result from disrupted blood flow in the choroidal vessels. Studies suggest that niacin may be used to treat AMD, but more well-designed studies are needed.

Alzheimer’s disease/ cognitive decline

Dementia can be caused by severe niacin insufficiency, but it is unclear whether variation in intake of niacin in the usual diet is linked to neurodegenerative decline or Alzheimer’s disease (AD). Further research is needed before a conclusion can be drawn.

Diabetes (Type 1/Type 2)

Niacinamide may prevent diabetes or delay the need for insulin. More research is needed to determine if niacinamide delays or prevents the onset of insulin dependence in individuals with type 1 diabetes. Niacin has been used to treat dyslipidemia associated with type 2 diabetes. However, this treatment has been controversial because it may worsen glycemic control. Patients should seek medical advice before starting niacin.


There is not enough information about the treatment or prevention of headaches with niacin. More research is needed.

High blood phosphorous level (hyperphosphatemia)

Niacinamide may reduce the high serum phosphate levels in hyperphosphatemia. However, more research is needed before niacinamide can be used to treat hyperphosphatemia.

Osteoarthritis (niacinamide)

Preliminary human studies suggest that niacinamide may be useful in the treatment of osteoarthritis. Further research is needed before a recommendation can be made.

Skin conditions

Niacinamide has been used in skin care products, including moisturizers, anti-aging products, and rosacea treatments. The benefits of niacinamide in skin care needs to be further studied before recommendations are made.

Type 1 diabetes mellitus prevention (niacinamide)

Niacinamide (not niacin) does not appear to delay the development of diabetes mellitus (type 1). Evidence is mixed and more study is needed in this area.


Posted in Atherosclerosis, Chiropractic, Grades, High-cholesterol, Mayo-Clinic, Research, Supplements | Tagged , , , , , , | 1 Comment

Methylsulfonylmethane (MSM) – Studies show benefits for the treatment of osteoarthritis.

Studies of MSM have suggested some benefits, particularly for treatment of osteoarthritis.

Methylsulfonylmethane (MSM) is an organosulfur compound with the formula (CH3)2SO2. It is also known by several other names including DMSO2, methyl sulfone, and dimethyl sulfone.[1] This colorless solid features the sulfonyl functional group and is considered relatively inert chemically. It occurs naturally in some primitive plants and is present in small amounts in many foods and beverages and it is marketed as a dietary supplement.


Evidence from clinical trials

Small-scale studies of possible treatments with MSM have been conducted on both animals and humans. These studies of MSM have suggested some benefits, particularly for treatment of osteoarthritis.


A review by S. Brien, P. Prescott, N. Bashir, H. Lewith and G. Lewith of the two small randomized controlled trials of methylsulfonylmethane in osteoarthritis knee pain relief[11][12] “reported significant improvement in pain outcomes in the treatment group compared to comparator treatments; however, methodological issues and concerns over optimal dosage and treatment period were highlighted.”[13]

The two trials included only 168 people, of whom 52 actually received the drug, so the review authors are careful to state: “No definitive conclusion can currently be drawn” and there is no “definitive evidence that MSM is superior to placebo in the treatment of mild to moderate osteoarthritis of the knee.”[13] While one of the two studies suggests that taking MSM for 12 weeks or less may be safe, “further research is needed to assess its safety for long-term use.”[14] Side effects of MSM ingestion include stomach upset, diarrhoea and headache.[14] In the absence of studies into dosage, longer-term safety and definitive efficacy trials, MSM must be considered experimental and should not be self-administered or prescribed outside clinical trials.[14]

After several reports that MSM helped arthritis in animal models, one study by P.R. Usha et al. had suggested that 1.5 g per day MSM (alone or in combination with glucosamine sulfate) was helpful in relieving symptoms of knee osteoarthritis.[12] The Usha clinical trial, however, was outsourced to India and conducted by researchers with little prior experience in clinical trials; tests were described without associated data, while some results were unsupported by the data that was shown. K.S. Jayaraman has warned that such outsourcing of clinical trials can be “rash” and “risky,” citing deficient ethics committees as well as an unethical approach to patient recruitment.[15]

Kim et al. conducted a second clinical trial of MSM for treatment of patients with osteoarthritis of the knee. Twenty-five patients took 6 g/day MSM and 25 patients took a placebo for 12 weeks. Ten patients did not complete the study, and intention to treat analysis was performed. Patients who took MSM reported reduced pain and improved physical function, but no evidence was found of a more general anti-inflammatory effect; there were no significant changes in two measures of systemic inflammation: C-reactive protein level and erythrocyte sedimentation rate.[11] Not counting an unpublished, no-control group trial by Lawrence, these two articles are the only clinical-trial support for MSM for osteoarthritis.


Posted in Chiropractic, Pain, Supplements | Tagged , , , , | 1 Comment

Muscle and Body Aches?

Muscle and Body Aches? –  Why not begin your chiropractic experience in the latest generation of relaxation technology with a state of the art zero-gravity deluxe massage chair.

Experience the ultimate relaxation of Swedish or Shiatsu-style massage with REAL Rollers. Now you can say goodbye to stress in this NASA-inspired near zero gravity position. Imagine countless hands and fingers slowly, continuously kneading and rolling your tired aching muscles. Powerful rolling wheels closely duplicate the hand movements of massage—kneading, stretching, tapping, rolling to de-stress stiff and achy muscles. You’re in heaven! Before you know it, all the day’s stress have melted away.

  • Zero gravity design
  • Designed with a set of S-track movable intelligent massage robot, special focus on the neck, shoulder and lumbar massage according to body curve
  • Automatically detect the whole body curve as well as make micro adjustments, which brings more humanistic and scientific massage enjoyment
  • Designed with six unique auto-programs: Healthcare, Relax, Therapy, Smart, Circulation and Demo
  • Automatic massage for the upper body (shoulder, neck, back and lumbar), the low body (buttock, thigh, calves and feet)
  • Manual massage for the upper body with three options, full body, partial and fixed
  • Six Massage styles – rolling, kneading, clapping, shiatsu, Swedish and combo
  • With five levels of speed & intensity
  • Three kinds of width adjustable settings, Wide, Medium and narrow
  • Air pressure massage for back (two airbags), with five intensity options
  • Air pressure for lower body (twenty-six airbags), with five intensity options
  • Powerful vibration massage for buttocks
  • Calf rest can be lifted and stretched, backrest can be lifted
  • LCD displayer
  • Auto timer 5-30 options
  • Wireless mini-controller
  • 32 air bags, 10 in the feet, 10 in the calves, 3 in the seat and 2 in the back. 2 in the shoulders, 3 neck & 3 in the hips
  • Air & Vibration Arm Massage
  • Hip Air Massage
  • Vibration Seat Massage
  • Lower Back Heat Therapy
  • Air Squeeze Neck massage
  • Shoulder Air Massage

Our office is fully equipped with these extraordinary massage chairs.  Located in Lansing, Illinois for over 60 years, Lansing Chiropractic Clinic is a leader in herniated disc treatment and pain management. Give us a call at 708-895-3228 to set up an appointment today.

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Glucosamine Sulfate Research – Double Blind Study

Glucosamine Sulfate Use and Delay of Progression of Knee Osteoarthritis

A 3-Year, Randomized, Placebo-Controlled, Double-blind Study

Karel Pavelká, MD, PhD; Jindriska Gatterová, MD; Marta Olejarová, MD; Stanislav Machacek, MD; Giampaolo Giacovelli, PhD; Lucio C. Rovati, MD 

Arch Intern Med. 2002;162:2113-2123.

Background  Conventional symptomatic treatments for osteoarthritis do not favorably affect disease progression. The aim of this randomized, placebo-controlled trial was to determine whether long-term (3-year) treatment with glucosamine sulfate can modify the progression of joint structure and symptom changes in knee osteoarthritis, as previously suggested.

Methods  Two hundred two patients with knee osteoarthritis (using American College of Rheumatology criteria) were randomized to receive oral glucosamine sulfate, 1500 mg once a day, or placebo. Changes in radiographic minimum joint space width were measured in the medial compartment of the tibiofemoral joint, and symptoms were assessed using the algo-functional indexes of Lequesne and WOMAC (Western Ontario and McMaster Universities).

Results  Osteoarthritis was of mild to moderate severity at enrollment, with average joint space widths of slightly less than 4 mm and a Lequesne index score of less than 9 points. Progressive joint space narrowing with placebo use was -0.19 mm (95% confidence interval, -0.29 to -0.09 mm) after 3 years.Conversely, there was no average change with glucosamine sulfate use (0.04 mm; 95% confidence interval, -0.06 to 0.14 mm), with a significant difference between groups (P = .001). Fewer patients treated with glucosamine sulfate experienced predefined severe narrowings (>0.5 mm): 5% vs 14% (P = .05). Symptoms improved modestly with placebo use but as much as 20% to 25% with glucosamine sulfate use, with significant final differences on the Lequesne index and the WOMAC total index and pain, function, and stiffness subscales. Safety was good and without differences between groups.

Conclusion  Long-term treatment with glucosamine sulfate retarded the progression of knee osteoarthritis, possibly determining disease modification.

From the Department of Medicine and Rheumatology, Charles University (Dr Pavelká), and the Institute of Rheumatology (Drs Pavelká, Gatterová, Olejarová, and Machacek), Prague, Czech Republic; and the Department of Clinical Pharmacology, Rotta Research Laboratorium, Monza, Italy (Drs Giacovelli and Rovati).

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Risk factors predictive of joint replacement in a 2-year multicentre clinical trial in knee osteoarthritis using MRI: results from over 6 years of observation
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Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI
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Buckland-Wright et al.
Rheumatology (Oxford) 2007;46:257-264.

A prospective randomised multicentre study comparing continuous and intermittent treatment with celecoxib in patients with osteoarthritis of the knee or hip
Luyten et al.
Ann Rheum Dis 2007;66:99-106.

Oral Glucosamine for 6 Weeks at Standard Doses Does Not Cause or Worsen Insulin Resistance or Endothelial Dysfunction in Lean or Obese Subjects
Muniyappa et al.
Diabetes 2006;55:3142-3150.

Glucosamine Supplementation Accelerates Early but Not Late Atherosclerosis in LDL Receptor-Deficient Mice
Tannock et al.
J. Nutr. 2006;136:2856-2861.

Effect of Glucosamine on Glucose Control
Stumpf and Lin
The Annals of Pharmacotherapy 2006;40:694-698.

Low levels of human serum glucosamine after ingestion of glucosamine sulphate relative to capability for peripheral effectiveness
Biggee et al.
Ann Rheum Dis 2006;65:222-226.

Chondroprotective drugs in degenerative joint diseases
Rheumatology (Oxford) 2006;45:129-138.

Comparison of quantitative and semiquantitative indicators of joint space narrowing in subjects with knee osteoarthritis
Mazzuca et al.
Ann Rheum Dis 2006;65:64-68.

Is it time for more rheumatologists to embrace osteoarthritis?
Birrell et al.
Rheumatology (Oxford) 2005;44:829-830.

Glucosamine Long-Term Treatment and the Progression of Knee Osteoarthritis: Systematic Review of Randomized Controlled Trials
Poolsup et al.
The Annals of Pharmacotherapy 2005;39:1080-1087.

A naturalistic study of the determinants of health related quality of life improvement in osteoarthritic patients treated with non-specific non-steroidal anti-inflammatory drugs
Rabenda et al.
Ann Rheum Dis 2005;64:688-693.

Chondroprotective activity of N-acetylglucosamine in rabbits with experimental osteoarthritis
Shikhman et al.
Ann Rheum Dis 2005;64:89-94.

Use of complementary medicines for osteoarthritis–a prospective study
Zochling et al.
Ann Rheum Dis 2004;63:549-554.

The use of conventional and complementary treatments for knee osteoarthritis in the community
Jordan et al.
Rheumatology (Oxford) 2004;43:381-384.

Non-surgical treatment of osteoarthritis: a half century of “advances”
Ann Rheum Dis 2004;63:117-122.

This house believes that we should advise our patients with osteoarthritis of the knee to take glucosamine
Manson and Rahman
Rheumatology (Oxford) 2004;43:100-101.

BMJ 2003;327:E182-182.

A topical cream containing glucosamine and chondroitin sulphate reduced joint pain in osteoarthritis of the knee
Evid. Based Med. 2003;8:154-154.

Structural and Symptomatic Efficacy of Glucosamine and Chondroitin in Knee Osteoarthritis: A Comprehensive Meta-analysis
Richy et al.
Arch Intern Med 2003;163:1514-1522.

Investigating CAM
CMAJ 2003;168:1527-1528.

Robin Goodfellow (42-1)
Rheumatology (Oxford) 2003;42:196-196.

BMJ 2002;325:1046-1046.

Is glucosamine worth taking for osteoarthritis?
DTB 2002;40:81-83.

Complementary medicine and the scientific method: Mainstreaming proven “alternative” therapies
AM J HOSP PALLIAT CARE 2002;19:369-371.

Posted in Chiropractic, Knee, osteoarthritis, Research, Supplements | Tagged , , , , , , , | Leave a comment

What is Glucosamine?



Glucosamine is a natural compound that is found in healthy cartilage. Glucosamine sulfate is a normal constituent of glycoaminoglycans in cartilage matrix and synovial fluid.

Available evidence from randomized controlled trials supports the use of glucosamine sulfate in the treatment of osteoarthritis, particularly of the knee. It is believed that the sulfate moiety provides clinical benefit in the synovial fluid by strengthening cartilage and aiding glycosaminoglycan synthesis. If this hypothesis is confirmed, it would mean that only the glucosamine sulfate form is effective and non-sulfated glucosamine forms are not effective.

Glucosamine is commonly taken in combination with chondroitin, a glycosaminoglycan derived from articular cartilage. Use of complementary therapies, including glucosamine, is common in patients with osteoarthritis, and may allow for reduced doses of non-steroidal anti-inflammatory agents.



These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.

Key to grades

 Grading rationale

Knee osteoarthritis (mild-to-moderate)

Based on human research, there is good evidence to support the use of glucosamine sulfate in the treatment of mild-to-moderate knee osteoarthritis. Most studies have used glucosamine sulfate supplied by one European manufacturer (Rotta Research Laboratorium), and it is not known if glucosamine preparations made by other manufacturers are equally effective. Although some studies of glucosamine have not found benefits, these have either included patients with severe osteoarthritis or used products other than glucosamine sulfate . The evidence for the effect of glycosaminoglycan polysulphate is conflicting and merits further investigation. More well-designed clinical trials are needed to confirm safety and effectiveness, and to test different formulations of glucosamine.

Osteoarthritis (general)

Several human studies and animal experiments report benefits of glucosamine in treating osteoarthritis of various joints of the body, although the evidence is less plentiful than that for knee osteoarthritis. Some of these benefits include pain relief, possibly due to an anti-inflammatory effect of glucosamine, and improved joint function. Overall, these studies have not been well designed. Although there is some promising research, more study is needed in this area before a firm conclusion can be made.


Chronic venous insufficiency

“Chronic venous insufficiency” is a syndrome that includes leg swelling, varicose veins, pain, itching, skin changes, and skin ulcers. The term is more commonly used in Europe than in the United States. Currently, there is not enough reliable scientific evidence to recommend glucosamine in the treatment of this condition.


Diabetes (and related conditions)

Early research suggests that glucosamine does not improve blood sugar control, lipid levels, or apolipoprotein levels in diabetics. Additional research is needed in this area.


Inflammatory bowel disease (Crohn’s disease, ulcerative colitis)

Preliminary research reports improvements with N-acetyl glucosamine as an added therapy in inflammatory bowel disease. Further scientific evidence is necessary before a strong recommendation can be made.


Pain (leg pain)

Preliminary human research reports benefits of injected glucosamine plus chondroitin in the treatment of leg pain arising from advanced lumbar degenerative disc disease. Further scientific evidence is necessary before a firm recommendation can be made.


Rehabilitation (after knee injury)

Glucosamine has been given to athletes with acute knee injuries. Although glucosamine did not improve pain, it did help improve flexibility. Additional research is needed to confirm these early findings.


Rheumatoid arthritis

Early human research reports benefits of glucosamine in the treatment of joint pain and swelling in rheumatoid arthritis. In other research, glucosamine did not exert anti-rheumatic effects, but it did improve symptoms of the disease. However, this is early information, and additional research is needed before a conclusion can be drawn. The treatment of rheumatoid arthritis can be complicated, and a qualified healthcare provider should follow patients with this disease.


Temporomandibular joint (TMJ) disorders

There is a lack of sufficient evidence to recommend for or against the use of glucosamine (or the combination of glucosamine and chondroitin) in the treatment of temporomandibular joint disorders.


High cholesterol

Glucosamine does not appear to alter LDL or HDL levels in patients with chronic joint pain or diabetes.


Posted in Chiropractic, Mayo-Clinic, osteoarthritis, Research, Supplements | Tagged , , , , , , | 1 Comment